Published research on Metronidazole

2 peer-reviewed publications on Metronidazole in oncology research, clinical work first, then laboratory studies. Each entry reports what the authors stated; follow the link for the full paper.

1. Clinical trial

   Radiation and nitroimidazoles in supratentorial high grade gliomas: a second clinical trial

   Urtasun R et al., British Journal of Cancer, 1982

   In 66 high-grade astrocytoma patients randomised to conventional radiation, large-fraction radiation with high-dose metronidazole, or the same with misonidazole, neither higher radiation dose nor the nitroimidazole sensitizers improved survival over conventional fractionated radiation.

2. Clinical trial

   Radiation and high-dose metronidazole in supratentorial glioblastomas

   Urtasun R et al., New England Journal of Medicine, 1976

   In 36 glioblastoma patients randomised to radiation alone or radiation with high-dose metronidazole as a hypoxic cell radiosensitizer, the metronidazole group showed a 4.5-month delay between relapse and death (P = 0.02), interpreted by the authors as a delay in tumour regrowth.

Metronidazole in the catalog (specifications, pack sizes, Certificate of Analysis)