Published research on Tinidazole

2 peer-reviewed publications on Tinidazole in oncology research, clinical work first, then laboratory studies. Each entry reports what the authors stated; follow the link for the full paper.

This page is a reading list of peer-reviewed publications, compiled for information. It is not a statement of indications, a recommendation or medical advice. Results from cell and animal studies do not translate into clinical use. Medsuvac products are supplied for their registered purposes; clinical decisions belong to a qualified physician.

Clinical trial
Radiosensitization by tinidazole: pharmacokinetic study

Cossu F et al., International Journal of Clinical Pharmacology Research, 1986

In radiotherapy patients, the highest tinidazole dose studied reached plasma and intratumoural concentrations comparable to those giving an in vitro radiosensitizing enhancement factor of about 1.5, and tolerance was reported as excellent.
In vivo
In vivo testing of hypoxic radiosensitizers using the KHT murine tumour assayed by the lung-colony technique

Rauth AM et al., British Journal of Radiology, 1975

Among eleven candidate hypoxic cell sensitizers tested in the KHT murine tumour, metronidazole and tinidazole given intraperitoneally produced an enhancement ratio of about 1.5 for chronically hypoxic cells in air-breathing mice.

Tinidazole in the catalog (specifications, pack sizes, Certificate of Analysis)